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Modified nucleosides and cancer

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Published by Springer-Verlag in Berlin, New York .
Written in English

Subjects:

  • Nucleosides -- Metabolism.,
  • Cancer.,
  • Nucleosides -- Metabolism.,
  • Neoplasms -- Metabolism.

Book details:

Edition Notes

Statementedited by Gisela Nass.
SeriesRecent results in cancer research = Fortschritte der Krebsforschung = Progrès dans les recherches sur le cancer ;, 84, Recent results in cancer research ;, 84.
ContributionsNass, Gisela.
Classifications
LC ClassificationsRC261 .R35 vol. 84, QP625.N88 .R35 vol. 84
The Physical Object
Paginationxii, 432 p. :
Number of Pages432
ID Numbers
Open LibraryOL3499143M
ISBN 100387120246
LC Control Number82019320

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  Purchase Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications, Volume 45C - 1st Edition. Print Book & E-Book. ISBN , Book Edition: 1. Modified Nucleosides and Cancer. Editors: Nass, G. (Ed.) Free Preview. Buy this book eB08 € price for Spain (gross) Buy eBook ISBN ; Digitally watermarked, DRM-free; Included format: PDF; Immediate eBook download after purchase . Recent results in cancer research = Fortschritte der Krebsforschung = Progrès dans les recherches sur le cancer ; 84 Notes "Lectures presented at the workshop Modified nucleosides and cancer held from 28 September to 2 October, in Freiburg, West Germany"--Pref. Get this from a library! Modified Nucleosides and Cancer. [Gisela Nass] -- This book comprises the lectures presented at the workshop Modified Nuc1eosides and Cancer held from 28 September to 2 October, in Freiburg, West Germany. The workshop was organized by Gisela.

ISBN: OCLC Number: Notes: "Lectures presented at the workshop Modified nucleosides and cancer held from 28 September to 2 October, in Freiburg, West Germany"--Preface. Search in this book series. Chromatography and Modification of Nucleosides Modified Nucleosides in Cancer and Normal Metabolism Methods and Applications. Edited by Charles W. Gehrke, Kenneth C.T. Kuo. Vol Part C, Pages iii-liv, C1-C () Download full volume. Previous volume. This chapter focuses on the mechanisms by which the post-transcriptional modifications regulate the codon recognition of tRNAs, primarily from the viewpoint of conformational characteristics of modified nucleosides. Post-transcriptional modifications are heavily involved in the specificities of codon recognition and also of aminoacylation.   The book contains a number of excellent individual chapters that offer a new and interesting perspective on the field I believe that this book will be an excellent resource for synthesis chemists looking for summaries of existing strategies to generate a wide range of modified nucleosides.

Part B has as its central theme the modified nucleosides of tRNA and the current analytical means for studying tRNA modifications. Modified nucleoside synthesis, function, structural conformation, biological regulation, and occurrence of modification in a wide range of tRNAs are presented, as is a chapter on DNA modification and a chapter on. This book comprises the lectures presented at the workshop Modified Nuc1eosides and Cancer held from 28 September to 2 October, in Freiburg, West Germany. The workshop was organized by Gisela Nass and sponsored by the Deutsche Forschungsgemeinschaft. Cancer, like other diseases accompanied by metabolic disorders, causes characteristic effects on cell turnover rate, activity of modifying enzymes, and RNA/DNA modifications. This results in an increased excretion of modified nucleosides in cancer patients. Therefore, for many years modified nucleosides have been suggested as tumor markers. I believe that this book will be an excellent resource for synthesis chemists looking for summaries of existing strategies to generate a wide range of modified nucleosides. Along that line, the more clinically based chapters provide good summaries of the biological activities of the modified nucleotides.